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levitra review Ar mediator of the nitric oxide pathway is cGMP. PDE catalyzes the degradation of cGMP. This pathway is active in numerous organ systems levitra review, and as of this writing levitra review, a number of different PDEs are known. The various PDEs differ in their physiologic roles and tissue distribution. Type 5 PDE is concentrated in the penile smooth muscle of the corpus cavernosum levitra review, where its normal function is to inhibit erection by degradation of cGMP levitra review, the mediator of erection. Viagra and the new drugs Cialis and Levitra all inhibit PDE-5 levitra review, which is an inhibitor for corporal smooth muscle relaxation levitra review, resulting in increased blood flow in the penis in response to sexual stimulation. Comp levitra review.
levitra review Arison of Viagra levitra review, Cialis levitra review, & Levitra No head-to-head trial comparing the 3 PDE inhibitors has been performed. However levitra review, some differences between the 3 are basic: a table has been created to illustrate the major differences. An obvious proviso is that extensive data are available on Viagra (more than 20 million men treated levitra review, more than 1100 peer-reviewed articles as of Feb. & 8217;03) levitra review, but only limited data on Cialis and Levitra. Drs. Gresser and Gleiter from the U. Tubingen in Germany have compared the three drugs via literature review (Eur. J. Med. Res. 7:435 levitra review, 2002) In brief levitra review, efficacy is approximately 70% with all 3 drugs. The side effect profile is similar among the 3 drugs levitra review, except that blue discoloration of vision (overlap with PDE-6 in the retina) is seen only with Viagra (<0.5%) and muscle aches only with Cialis (~5%). Otherwise levitra review, vasodilatory side effects (headaches levitra review, nasal congestion levitra review, flushing) are common with all levitra review, but are mild levitra review, and only rarely cause men to drop out of clinical trials (2-3% quit rate). All 3 will carry a contra-indication in men using organic nitrates. Otherwise levitra review, the long half-life of Cialis (17.5 hours) is noteworthy levitra review, earning this drug the nickname & 8216;weekender levitra review, & 8217; as a single dose taken on Friday would still be exerting an effect Sunday (or even Monday). Conclusion Alternative .
levitra review Among the 3 drugs levitra review, except that blue discoloration of vision (overlap with PDE-6 in the retina) is seen only with Viagra (<0.5%) and muscle aches only with Cialis (~5%). Otherwise levitra review, vasodilatory side effects (headaches levitra review, nasal congestion levitra review, flushing) are common with all levitra review, but are mild levitra review, and only rarely cause men to drop out of clinical trials (2-3% quit rate). All 3 will carry a contra-indication in men using organic nitrates. Otherwise levitra review, the long half-life of Cialis (17.5 hours) is noteworthy levitra review, earning this drug the nickname & 8216;weekender levitra review, & 8217; as a single dose taken on Friday would still be exerting an effect Sunday (or even Monday). Conclusion Alternative P.
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