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) is that it preserves the elevated levels of cGMP that are created when a man is sexually stimulated for a stronger, more lasting erection.That's how Cialis works - Cialis blocks the enzyme phosphodiesterase-5 (PDE5) which is responsible for the neutralization of cGMP. Cialis (tadalafil) is a highly selective inhibitor of PDE5. (PDE5 is not the only phosphodiesterase involved in the erectile physiology but it appears to be the most important one). The nice thing about PDE5 blockers is that they shouldn& 39;t cause erections at inappropriate times because they only block degradation of cGMP produced in reaction to sexual stimulation, such as thinking about something sexy. If you are not being sexually stimulated, there is no cGMP to protect, so the drug remains in the background.How Does Cialis Compare To Viagra and Levitra?Cialis Versus ViagraCialis Versus Viagra From Forbes magazine 12 03 03; M. Herper; side by side comparison of various characteristics of Cialis and Viagra in slide show format.Cialis Versus Viagra Versus LevitraViagra Faces Stiff Competition On Airwaves … Viagra focuses on depicting happy men in their ads. Levitra uses a woman& 39;s testimonial and sports star Mike Ditka. Cialis, which is more subtle and longer-lasting, focuses on the relationship … & 91; WFTV.com& 93;Editor's Note: Above report offers comparison between Cialis, Viagra and Levitra in terms of advertising.Absorption, Onset, Bioavailability Cialis is readily absorbed from the bloodstream. It is about 16& 37; bioavailable. Tadalafil is about 94& 37; bound to plasma protein. Maximum plasma c

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